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Numb3rs is a drama about an F.B.I agent who recruits his mathematical-genius brother to help the Bureau solve a wide range of challenging crimes in Los Angeles. The two brothers take on the most confounding criminal cases from a very distinctive perspective. Inspired by actual cases, the series depicts how the confluence of police work and mathematics provides unexpected revelations and answers to the most perplexing criminal questions.

A dedicated FBI agent, Don Eppes (Rob Morrow), couldn't be more different from his younger brother, Charlie (David Krumholtz), a brilliant mathematician who, since he was little, yearned to impress his big brother. As a seasoned investigator, Don deals in hard facts and evidence, whereas Charlie, a math professor at a California university, functions in a world of mathematical probability and equations. Now, despite their disparate approaches to life, Don and Charlie are able to combine their areas of expertise and solve some killer cases...